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Mouse anti-Mucin 5AC, Clone: 45M1, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21519602MG

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 Disclaimers

For Research Use Only

Catalog No. NBP21519602

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Description & Specifications

Specifications

Formulation PBS with 0.05% BSA. Protein G purified.
Host Species Mouse
Isotype IgG1, κ
Quantity 0.2mg
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Conjugate Unlabeled
Cross Reactivity Chicken
Cross Reactivity Feline
Cross Reactivity Hedgehog
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Porcine
Cross Reactivity Primate
Cross Reactivity Rabbit
Cross Reactivity Rat
Antigen Mucin 5AC
Format Purified
Gene Accession No. P98088
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Immunogen MUC5AC isolated from the fluid of an ovarian mucinous cyst from an O Le(a-b-) patient was used as immunogen to generate the MUC5AC antibody.
Purification Method Purified
Regulatory Status RUO
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 4586
Test Specificity This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins. Does not react to Bovine.
Clone 45M1
Concentration 0.2mg/mL