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Mouse anti-Mucin 5AC, Clone: 45M1, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21519601MG

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 Disclaimers

For Research Use Only

Catalog No. NBP21519601

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Description & Specifications

Specifications

Cross Reactivity Chicken
Cross Reactivity Feline
Cross Reactivity Hedgehog
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Porcine
Cross Reactivity Primate
Cross Reactivity Rabbit
Cross Reactivity Rat
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Quantity 0.1mg
Format Purified
Immunogen MUC5AC isolated from the fluid of an ovarian mucinous cyst from an O Le(a-b-) patient was used as immunogen to generate the MUC5AC antibody.
Host Species Mouse
Gene Accession No. P98088
Primary or Secondary Primary
Isotype IgG1, κ
Antigen Mucin 5AC
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Formulation PBS with 0.05% BSA. Protein G purified.
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Concentration 0.2mg/mL
Test Specificity This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins. Does not react to Bovine.
Purification Method Purified
Regulatory Status RUO
Clone 45M1
Gene ID (Entrez) 4586