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Mouse anti-Mucin 5AC, Clone: 45M1, Novus Biologicals™

Manufacturer:  Novus Biologicals Canada NBP21519601MG

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Catalog No. NBP21519601


 

Disclaimers:

For Research Use Only


Specifications Description & Specifications

Specifications

Mucin 5AC
45M1
Unlabeled
PBS with 0.05% BSA. Protein G purified.
Murine
IgG1, κ
0.1mg
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Monoclonal
This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins. Does not react to Bovine.
ELISA,Flow Cytometry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Frozen),Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blot
0.2mg/mL
Purified
P98088
MUC5AC isolated from the fluid of an ovarian mucinous cyst from an O Le(a-b-) patient was used as immunogen to generate the MUC5AC antibody.
Purified
RUO
Primary
4586
Chicken,Feline,Hedgehog,Human,Murine,Porcine,Primate,Rabbit,Rat