Please login to your online account to display your discounted pricing

Mouse anti-Mucin 5AC, Clone: 45M1, Azide Free, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23273202MG

 View more versions of this product

 Disclaimers

For Research Use Only

Catalog No. NBP23273202

  • / Each
 

Description & Specifications

Specifications

Antigen Mucin 5AC
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Clone 45M1
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Chicken
Cross Reactivity Feline
Cross Reactivity Hedgehog
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Porcine
Cross Reactivity Primate
Cross Reactivity Rabbit
Cross Reactivity Rat
Format Purified
Formulation 10mM PBS. Does not contain BSA. Protein G purified.
Gene Accession No. P98088
Host Species Mouse
Immunogen MUC5AC isolated from the fluid of an ovarian mucinous cyst from an O Le(a-b-) patient was used as immunogen to generate the MUC5AC antibody.
Isotype IgG1, κ
Purification Method Purified
Quantity 0.2mg
Regulatory Status RUO
Storage Requirements Store at -80°C. Avoid freeze-thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 4586
Test Specificity This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins. Does not react to Bovine.