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Mouse anti-Melan-A/MART-1, Clone: SPM342, Azide Free, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23476501MG

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 Disclaimers

For Research Use Only

Catalog No. NBP23476501

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Description & Specifications

Specifications

Quantity 0.1mg
Antigen Melan-A/MART-1
Format Purified
Formulation 10mM PBS. Does not contain BSA. Azide Free.
Host Species Mouse
Applications ELISA
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Immunogen Recombinant hMART-1 protein
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Test Specificity This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Does not react with Mouse or Rat.
Reconstitution Protein A purified
Clone SPM342
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Gene Accession No. Q16655
Isotype IgG2b, κ
Purification Method Purified
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Primary or Secondary Primary
Gene ID (Entrez) 2315