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Mouse anti-Melan-A/MART-1, Clone: SPM342, Azide Free, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23476501MG

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 Disclaimers

For Research Use Only

Catalog No. NBP23476501

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Description & Specifications

Specifications

Quantity 0.1mg
Conjugate Unlabeled
Applications ELISA
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Formulation 10mM PBS. Does not contain BSA. Azide Free.
Cross Reactivity Human
Format Purified
Reconstitution Protein A purified
Clone SPM342
Antigen Melan-A/MART-1
Immunogen Recombinant hMART-1 protein
Concentration 1mg/mL
Host Species Mouse
Test Specificity This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Does not react with Mouse or Rat.
Gene Accession No. Q16655
Isotype IgG2b, κ
Gene ID (Entrez) 2315
Primary or Secondary Primary
Purification Method Purified
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.