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Mouse anti-Melan-A/MART-1, Clone: M2-9E3, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21519802MG

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 Disclaimers

For Research Use Only

Catalog No. NBP21519802

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Description & Specifications

Specifications

Antigen Melan-A/MART-1
Format Purified
Conjugate Unlabeled
Formulation PBS with 0.05% BSA. Protein G purified.
Gene Accession No. Q16655
Host Species Mouse
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Immunogen Recombinant human Melan-A protein was used as immunogen to generate the Melan-A antibody.
Purification Method Purified
Quantity 0.2mg
Regulatory Status RUO
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Monoclonal or Polyclonal Monoclonal
Test Specificity This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Concentration 0.2mg/mL
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Isotype IgG2b, κ
Primary or Secondary Primary
Gene ID (Entrez) 2315
Clone M2-9E3