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Mouse anti-Melan-A/MART-1, Clone: M2-9E3, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21519801MG

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 Disclaimers

For Research Use Only

Catalog No. NBP21519801

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Description & Specifications

Specifications

Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Isotype IgG2b, κ
Quantity 0.1mg
Antigen Melan-A/MART-1
Gene ID (Entrez) 2315
Primary or Secondary Primary
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Purified
Clone M2-9E3
Gene Accession No. Q16655
Immunogen Recombinant human Melan-A protein was used as immunogen to generate the Melan-A antibody.
Test Specificity This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Regulatory Status RUO
Purification Method Purified
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Concentration 0.2mg/mL
Formulation PBS with 0.05% BSA. Protein G purified.
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.