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Mouse anti-Kappa Light Chain, Clone: L1C1, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21519101MG

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 Disclaimers

For Research Use Only

Catalog No. NBP21519101

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Description & Specifications

Specifications

Antigen Kappa Light Chain
Applications ELISA
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Clone L1C1
Concentration 0.2mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Purified
Formulation PBS with 0.05% BSA. Protein G purified.
Gene Accession No. P01601
Host Species Mouse
Immunogen B lymphoma cells
Isotype IgG1, κ
Purification Method Purified
Quantity 0.1mg
Regulatory Status RUO
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 3514
Test Specificity This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.