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Mouse anti-HLA-DR, Clone: LN-3, Azide Free, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23467602MG

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 Disclaimers

For Research Use Only

Catalog No. NBP23467602

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Description & Specifications

Specifications

Cross Reactivity Human
Cross Reactivity Primate
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Conjugate Unlabeled
Regulatory Status RUO
Formulation 10mM PBS. Does not contain BSA. Azide Free.
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 3122
Purification Method Purified
Format Purified
Host Species Mouse
Primary or Secondary Primary
Immunogen Activated human peripheral blood mononuclear cells
Test Specificity This MAb reacts with the beta-chain of HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each other's respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Does not react with Mouse.
Quantity 0.2mg
Antigen HLA-DR
Gene Accession No. P01903
Concentration 1mg/mL
Storage Requirements Store at -20 to -80°C. Avoid freeze-thaw cycles.
Reconstitution Protein A purified
Clone LN-3
Isotype IgG2b, κ