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Mouse anti-HLA-DR, Clone: LN-3, Azide Free, Novus Biologicals™

Manufacturer:  Novus Biologicals Canada NBP23467601MG

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Catalog No. NBP23467601


 

Disclaimers:

For Research Use Only


Specifications Description & Specifications

Specifications

HLA-DR
LN-3
Unlabeled
10mM PBS. Does not contain BSA. Azide Free.
Murine
IgG2b, κ
0.1mg
Store at -20 to -80°C. Avoid freeze-thaw cycles.
Monoclonal
This MAb reacts with the beta-chain of HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each other's respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Does not react with Mouse.
Human,Primate
ELISA,Flow Cytometry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Frozen),Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blot
1mg/mL
Purified
P01903
Activated human peripheral blood mononuclear cells
Purified
RUO
Primary
3122
Protein A purified