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Mouse anti-Cytokeratin, HMW, Clone: 34BE12, Novus Biologicals™

Manufacturer: novus biologicals canada  NBP22941701ML

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For Research Use Only

Catalog No. NBP22941701


Description & Specifications


Antigen Cytokeratin, HMW
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Clone 34bE12
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Formulation Culture Medium. Bioreactor concentrate.
Gene Accession No. P13646
Host Species Mouse
Immunogen Solublized keratin extract from human stratum corneum was used as the immunogen for the Cytokeratin 34bE12 antibody.
Isotype IgG1
Purification Method Concentrated
Quantity 0.1mL
Regulatory Status RUO
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 51350
Test Specificity This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands; there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations.