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Mouse anti-Cytokeratin 19, Clone: A53-B/A2.26, Novus Biologicals™

Manufacturer:  Novus Biologicals Canada NBP21518601MG

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Catalog No. NBP21518601


 

Disclaimers:

For Research Use Only


Specifications Description & Specifications

Specifications

Cytokeratin 19
A53-B/A2.26
Unlabeled
PBS with 0.05% BSA. Protein G purified.
Murine
IgG2a, κ
0.1mg
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Monoclonal
This MAb reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. Its epitope maps between amino acid 312-335. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer. The A53-B antibody strongly binds to human Keratin-19 and weakly binds to mouse, rat and guinea pig Keratin-19.
ELISA,Flow Cytometry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Frozen),Immunohistochemistry (Paraffin),Immunoprecipitation,Western Blot
0.2mg/mL
Purified
P08727
Human breast cancer MCF-7 cells were used as the immunogen for the Keratin-19 antibody.
Purified
RUO
Primary
3880
Human