Please login to your online account to display your discounted pricing

Mouse anti-Cyclin D1, Clone: DCS-6, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21518902MG

 View more versions of this product

 Disclaimers

For Research Use Only

Catalog No. NBP21518902

  • / Each
 

Description & Specifications

Specifications

Antigen Cyclin D1
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blot
Clone DCS-6
Concentration 0.2mg/mL
Conjugate Unlabeled
Format Purified
Formulation PBS with 0.05% BSA. Protein G purified.
Gene Accession No. P24385
Host Species Murine
Immunogen Human recombinant full length Cyclin D1 protein was used as immunogen to generate this antibody.
Isotype IgG2a, κ
Purification Method Purified
Quantity 0.2mg
Regulatory Status RUO
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 595
Test Specificity Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Target Species Human
Target Species Murine
Target Species Primate
Target Species Rat