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Mouse anti-CD43/Sialophorin, Clone: DF-T1, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21519002MG

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 Disclaimers

For Research Use Only

Catalog No. NBP21519002

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Description & Specifications

Specifications

Antigen CD43/Sialophorin
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Clone DF-T1
Concentration 0.2mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Purified
Formulation PBS with 0.05% BSA. Protein G purified.
Gene Accession No. P16150
Host Species Mouse
Immunogen Myeloblastic KG1 cells were used as the immunogen for this antibody.
Isotype IgG1, κ
Purification Method Purified
Quantity 0.2mg
Regulatory Status RUO
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 6693
Test Specificity It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.