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Mouse anti-CD43/Sialophorin, Clone: DF-T1, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21519002MG

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 Disclaimers

For Research Use Only

Catalog No. NBP21519002

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Description & Specifications

Specifications

Gene Accession No. P16150
Concentration 0.2mg/mL
Antigen CD43/Sialophorin
Format Purified
Formulation PBS with 0.05% BSA. Protein G purified.
Host Species Mouse
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Immunogen Myeloblastic KG1 cells were used as the immunogen for this antibody.
Isotype IgG1, κ
Regulatory Status RUO
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 6693
Test Specificity It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Conjugate Unlabeled
Purification Method Purified
Quantity 0.2mg
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clone DF-T1
Cross Reactivity Human