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Mouse anti-CD43/Sialophorin, Clone: DF-T1, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21519001MG

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 Disclaimers

For Research Use Only

Catalog No. NBP21519001

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Description & Specifications

Specifications

Antigen CD43/Sialophorin
Host Species Mouse
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Immunogen Myeloblastic KG1 cells were used as the immunogen for this antibody.
Quantity 0.1mg
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Format Purified
Formulation PBS with 0.05% BSA. Protein G purified.
Gene Accession No. P16150
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 6693
Clone DF-T1
Concentration 0.2mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Isotype IgG1, κ
Purification Method Purified
Primary or Secondary Primary
Test Specificity It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.