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Mouse anti-CD31/PECAM-1, Clone: JC/70A, Azide Free, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP23465101MG

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 Disclaimers

For Research Use Only

Catalog No. NBP23465101

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Description & Specifications

Specifications

Primary or Secondary Primary
Clone JC/70A
Conjugate Unlabeled
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Purification Method Purified
Antigen CD31/PECAM-1
Format Purified
Gene Accession No. P16284
Host Species Mouse
Immunogen Membrane preparation of a spleen from a patient with hairy cell leukemia (JC/70A)
Isotype IgG1, κ
Quantity 0.1mg
Regulatory Status RUO
Storage Requirements Store at -20 to -80°C. Avoid freeze-thaw cycles.
Gene ID (Entrez) 5175
Cross Reactivity Cynomolgus
Cross Reactivity Human
Cross Reactivity Monkey
Cross Reactivity Rabbit
Formulation 10mM PBS. Does not contain BSA. Azide Free.
Monoclonal or Polyclonal Monoclonal
Test Specificity CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence. Porcine (Negative), Rat (Negative).
Reconstitution Protein A purified
Concentration 1mg/mL