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Mouse anti-CD31/PECAM-1, Clone: C31.7, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21518801MG

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 Disclaimers

For Research Use Only

Catalog No. NBP21518801

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Description & Specifications

Specifications

Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Primary or Secondary Primary
Gene ID (Entrez) 5175
Quantity 0.1mg
Formulation PBS with 0.05% BSA. Protein G purified.
Host Species Mouse
Clone C31.7
Concentration 0.2mg/mL
Format Purified
Cross Reactivity Human
Cross Reactivity Primate
Cross Reactivity Rabbit
Purification Method Purified
Gene Accession No. P16284
Antigen CD31/PECAM-1
Regulatory Status RUO
Isotype IgG1, κ
Immunogen Membrane preparation of a spleen from a patient with hairy cell leukemia.
Storage Requirements Store at 4°C. Do not freeze.
Test Specificity CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence. Cynomolgus Monkey was specifically tested for primate. Feedback has been negative on pig kidney paraffin sections.