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Mouse anti-CA19-9, Clone: 121SLE, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21518210ML

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 Disclaimers

For Research Use Only

Catalog No. NBP21518210

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Description & Specifications

Specifications

Cross Reactivity Human
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Antigen CA19-9
Gene ID (Entrez) 3362
Conjugate Unlabeled
Gene Accession No. P50406
Primary or Secondary Primary
Formulation Culture Medium. Bioreactor concentrate.
Purification Method Concentrated
Isotype IgM, κ
Regulatory Status RUO
Immunogen Precipitin lines obtained after immunodiffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A+B- patient (0Le) were used as immunogen for this CA19-9 antibody.
Format Concentrated
Clone 121SLE
Test Specificity CA19-9, a carbohydrate epitope expressed on a high MW (>400kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is superb for staining of formalin-fixed, paraffin-embedded tissues.
Quantity 1mL