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Mouse anti-CA19-9, Clone: 121SLE, Novus Biologicals™

Manufacturer: novus biologicals canada  NBP21518201ML

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For Research Use Only

Catalog No. NBP21518201


Description & Specifications


Antigen CA19-9
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Clone 121SLE
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Formulation Culture Medium. Bioreactor concentrate.
Gene Accession No. P50406
Host Species Mouse
Immunogen Precipitin lines obtained after immunodiffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A+B- patient (0Le) were used as immunogen for this CA19-9 antibody.
Isotype IgM, κ
Purification Method Concentrated
Quantity 0.1mL
Regulatory Status RUO
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 3362
Test Specificity CA19-9, a carbohydrate epitope expressed on a high MW (>400kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is superb for staining of formalin-fixed, paraffin-embedded tissues.