Please login to your online account to display your discounted pricing

Mouse anti-Bcl-2, Clone: 100/D5, Novus Biologicals™


Manufacturer: novus biologicals canada  NBP21520001MG

 View more versions of this product

 Disclaimers

For Research Use Only

Catalog No. NBP21520001

  • / Each
 

Description & Specifications

Specifications

Antigen Bcl-2
Applications ELISA
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Western Blotting
Clone 100/D5
Concentration 0.2mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Purified
Formulation PBS with 0.05% BSA. Protein G purified.
Gene Accession No. P10415
Host Species Mouse
Immunogen 1990).
Isotype IgG1, κ
Purification Method Purified
Quantity 0.1mg
Regulatory Status RUO
Storage Requirements Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 596
Test Specificity This antibody recognizes a protein of 25-26kDa, identified as the bcl-2alpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2alpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative. Does not react with Mouse or Rat.
Reconstitution Outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes.