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Molecular Probes™ Thapsigargin DFS Item


Tumor promoter

Manufacturer: life technologies  T7459

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Catalog No. T7459

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Description & Specifications

Specifications

Quantity 20 x 50μg
Storage Requirements Store in freezer (-5° to -30°C)
Product Type Promoter, Tumor

Thapsigargin is a naturally occurring sesquiterpene lactone isolated from the umbelliferous plant Thapsia garganica. This tumor promoter releases Ca2++ from intracellular stores by specifically inhibiting the endoplasmic reticulum Ca2++-ATPase. It does not directly affect plasma membrane Ca2++-ATPases, Ins 1,4,5-P3 production or protein kinase C activity.

Cell Analysis, Cell Structure, Cellular Imaging, Immunofluorescence (IF), Immunofluorescence Staining and Detection, Receptors