Thermo Scientific™ Lab Vision™ MMP-2 (72kDa Collagenase IV) Ab-7, Rabbit Polyclonal Antibody
Produce accurate, reproducible results with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-7, Rabbit Polyclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ RB1537PABX
Produce accurate, reproducible results with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-7, Rabbit Polyclonal Antibody.MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids.
Host Species: Rabbit
Species Reactivity: Human, Mouse, Rat and Cow. Others not known.
Epitope: Second half of MMP-2
Immunogen: A synthetic peptide from the second half of human MMP-2
Molecular Weight: 72kDa (proform) and ∽66kDa (active form)
Positive Control: Conditioned, serum-free medium from (TPA-treated) HFl-1 cells
Cellular Localization: Cytoplasmic
- Western Blotting
USA: RUO; Int'l: RUO
|MMP-2 (72kDa Collagenase IV) Ab-7|
|A synthetic peptide from the second half of human MMP-2|
|Proteases And Inhibitors|
|Ab without BSA/Azide (Frozen)|