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Thermo Scientific™ Lab Vision™ MMP-2 (72kDa Collagenase IV) Ab-7, Rabbit Polyclonal Antibody


Produce accurate, reproducible results with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-7, Rabbit Polyclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RB1537PABX

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Catalog No. RB1537PABX

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Description & Specifications

Specifications

Antigen MMP-2 (72kDa Collagenase IV) Ab-7
Applications Western Blotting
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen A synthetic peptide from the second half of human MMP-2
Isotype IgG
Quantity 1mL
Regulatory Status RUO
Research Discipline Proteases And Inhibitors
Type Primary

Produce accurate, reproducible results with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-7, Rabbit Polyclonal Antibody.

MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat and Cow. Others not known.

Epitope: Second half of MMP-2

Immunogen: A synthetic peptide from the second half of human MMP-2

Molecular Weight: 72kDa (proform) and ∽66kDa (active form)

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFl-1 cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Western Blotting

Note:

USA: RUO; Int'l: RUO