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Thermo Scientific™ Lab Vision™ MMP-2 (72kDa Collagenase IV) Ab-7, Rabbit Polyclonal Antibody


Produce accurate, reproducible results with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-7, Rabbit Polyclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RB1537PABX

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Catalog No. RB1537PABX

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Description & Specifications

Specifications

Antigen MMP-2 (72kDa Collagenase IV) Ab-7
Applications Western Blot
Classification Polyclonal
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Human
Cross Reactivity Mouse
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Rabbit
Immunogen A synthetic peptide from the second half of human MMP-2
Isotype IgG
Quantity 1mL
Regulatory Status RUO
Research Discipline Proteases And Inhibitors
Type Primary
Monoclonal or Polyclonal Polyclonal
Target Species Bovine
Target Species Human
Target Species Murine

Produce accurate, reproducible results with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-7, Rabbit Polyclonal Antibody.

MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat and Cow. Others not known.

Epitope: Second half of MMP-2

Immunogen: A synthetic peptide from the second half of human MMP-2

Molecular Weight: 72kDa (proform) and ∽66kDa (active form)

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFl-1 cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Western Blotting

Note:

USA: RUO; Int'l: RUO