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Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-4, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-4, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™  MS806P1ABX

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Catalog No. MS806P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen MMP-2 (72kDa Collagenase IV) Ab-4
Classification Monoclonal
Clone A-Gel VC2
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Murine
Immunogen Human APMA-activated native 72kDa MMP-2
Isotype IgG1
Quantity 100μL
Regulatory Status RUO
Research Discipline Proteases And Inhibitors
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human

Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-4, Mouse Monoclonal Antibody.

MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids.

Host Species: Mouse

Clone: A-Gel VC2

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Human APMA-activated native 72kDa MMP-2

Molecular Weight: 72kDa (proform) and ∽66kDa (active form)

Positive Control: Placenta; Bladder, breast and ovarian CAs

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (not qualified)

Note:

USA: RUO; Int'l: RUO