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Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-4, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-4, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ MS806P1ABX

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Catalog No. MS806P1ABX


 

Specifications

Description

Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-4, Mouse Monoclonal Antibody.

MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids.

Host Species: Mouse

Clone: A-Gel VC2

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Human APMA-activated native 72kDa MMP-2

Molecular Weight: 72kDa (proform) and ∽66kDa (active form)

Positive Control: Placenta; Bladder, breast and ovarian CAs

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (not qualified)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

MMP-2 (72kDa Collagenase IV) Ab-4
A-Gel VC2
Unlabeled
Murine
IgG1
RUO
Primary
Human
Monoclonal
1mg/mL
Concentrated
Human APMA-activated native 72kDa MMP-2
100μL
Proteases And Inhibitors
Monoclonal