Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ MMP-2 (72kDa Collagenase IV) Ab-2, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-2, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS804P1ABX

 View more versions of this product

Catalog No. MS804P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen MMP-2 (72kDa Collagenase IV) Ab-2
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone VB3
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen Human native 72kDa MMP-2
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Proteases And Inhibitors
Type Primary

Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-2, Mouse Monoclonal Antibody.

MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids.

Host Species: Mouse

Clone: VB3

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Human native 72kDa MMP-2

Molecular Weight: 72kDa (proform) and ∽66kDa (active form)

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Not Suitable)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO