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Thermo Scientific™ Lab Vision™ MMP-2 (72kDa Collagenase IV) Ab-2, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-2, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS804P1ABX

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Catalog No. MS804P1ABX

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Description & Specifications

Specifications

Antigen MMP-2 (72kDa Collagenase IV) Ab-2
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone VB3
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Murine
Immunogen Human native 72kDa MMP-2
Isotype IgG2a kappa
Quantity 100μL
Regulatory Status RUO
Research Discipline Proteases And Inhibitors
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human

Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-2, Mouse Monoclonal Antibody.

MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids.

Host Species: Mouse

Clone: VB3

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Human native 72kDa MMP-2

Molecular Weight: 72kDa (proform) and ∽66kDa (active form)

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Not Suitable)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO