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Thermo Scientific™ Lab Vision™ MMP-2 (72kDa Collagenase IV) Ab-1, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS567P1ABX

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Catalog No. MS567P1ABX

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Description & Specifications

Specifications

Antigen MMP-2 (72kDa Collagenase IV) Ab-1
Applications Western Blotting
Classification Monoclonal
Clone CA-4001 or CA719E3C
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Host Species Mouse
Immunogen N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV
Isotype IgG1
Quantity 100µL
Regulatory Status RUO
Research Discipline Proteases And Inhibitors
Type Primary

Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-1, Mouse Monoclonal Antibody.

MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids into an active form.of 62kDa.

Host Species: Mouse

Clone: CA-4001 or CA719E3C

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: N-terminal (APSPIIKFPGD-VAPKTDK)

Immunogen: N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV

Molecular Weight: 72kDa (proform)

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Not suitable)
  • Inhibition of MMP-2 Activity

Note:

USA: RUO; Int'l: RUO