Thermo Scientific™ Lab Vision™ MMP-2 (72kDa Collagenase IV) Ab-1, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS567P1ABX
Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-1, Mouse Monoclonal Antibody.MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids into an active form.of 62kDa.
Host Species: Mouse
Clone: CA-4001 or CA719E3C
Species Reactivity: Human, Mouse and Rat. Others not known.
Epitope: N-terminal (APSPIIKFPGD-VAPKTDK)
Immunogen: N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV
Molecular Weight: 72kDa (proform)
Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells
Cellular Localization: Cytoplasmic
- Western Blotting
- Immunoprecipitation (Not suitable)
- Inhibition of MMP-2 Activity
USA: RUO; Int'l: RUO
|MMP-2 (72kDa Collagenase IV) Ab-1|
|N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV|
|Proteases And Inhibitors|
|CA-4001 or CA719E3C|