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Thermo Scientific™ Lab Vision™ MMP-2 (72kDa Collagenase IV) Ab-1, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS567P1ABX

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Catalog No. MS567P1ABX

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Description & Specifications

Specifications

Antigen MMP-2 (72kDa Collagenase IV) Ab-1
Applications Western Blot
Classification Monoclonal
Clone CA-4001 or CA719E3C
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Host Species Murine
Immunogen N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV
Isotype IgG1
Quantity 100μL
Regulatory Status RUO
Research Discipline Proteases And Inhibitors
Type Primary
Monoclonal or Polyclonal Monoclonal
Target Species Human
Target Species Murine
Target Species Rat

Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MMP-2 (72kDa Collagenase IV) Ab-1, Mouse Monoclonal Antibody.

MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-2; also known as 72kDa collagenase IV or gelatinase A is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids into an active form.of 62kDa.

Host Species: Mouse

Clone: CA-4001 or CA719E3C

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: N-terminal (APSPIIKFPGD-VAPKTDK)

Immunogen: N-terminal peptide APSPIIKFPGD-VAPKTDK of procollagenase IV

Molecular Weight: 72kDa (proform)

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Not suitable)
  • Inhibition of MMP-2 Activity

Note:

USA: RUO; Int'l: RUO