missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ MMP-1 (Collagenase-1) Ab-6, Rabbit Polyclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with the Thermo Scientific™ MMP-1 (Collagenase-1) Ab-6, Rabbit Polyclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ RB1536PABX

 View more versions of this product

Catalog No. RB1536PABX


 

Specifications

Description

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with the Thermo Scientific™ MMP-1 (Collagenase-1) Ab-6, Rabbit Polyclonal Antibody.

Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading connective tissue components. Imbalanced secretion of certain MMP or disturbances in the differential control of MMP by tissue inhibitor of MMPs (TIMPs) are implicated in the invasive potential of malignant tumors. Interstitial collagenase (MMP-1), 72kDa gelatinase A/type IV collagenase (MMP-2), and 92kDa gelatinase B/type IV collagenase (MMP-9) dissolve extracellular matrix (ECM) and may initiate and promote angiogenesis.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Does not react with cow. Others not known.

Epitope: Middle region of MMP-1

Immunogen: A synthetic peptide from the middle region of the human MMP-1

Molecular Weight: 52kDa (unglycosylated) and 57kDa (glycosylated) species of proform of MMP-1 plus 42kDa (unglycosylated) and 47kDa (glycosylated) active form of MMP-1

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells; Placenta; Bladder, breast, ovarian, colon CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

MMP-1 (Collagenase-1) Ab-6
Polyclonal
Unlabeled
Concentrated
Rabbit
IgG
RUO
Primary
Human
Immunohistochemistry (Paraffin)
1mg/mL
Human
Ab without BSA/Azide (Frozen)
A synthetic peptide from the middle region of the human MMP-1
1mL
Proteases And Inhibitors
Polyclonal