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Thermo Scientific™ Lab Vision™ MMP-1 (Collagenase-1) Ab-6, Rabbit Polyclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with the Thermo Scientific™ MMP-1 (Collagenase-1) Ab-6, Rabbit Polyclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  RB1536P1ABX

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Catalog No. RB1536P1ABX

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Description & Specifications

Specifications

Quantity 500µL
Immunogen A synthetic peptide from the middle region of the human MMP-1
Host Species Rabbit
Format Concentrated
Cross Reactivity Human
Regulatory Status RUO
Antigen MMP-1 (Collagenase-1) Ab-6
Applications Immunohistochemistry (Paraffin)
Isotype IgG
Conjugate Unlabeled
Classification Polyclonal
Formulation Ab without BSA/Azide (Frozen)
Concentration 1mg/mL
Type Primary
Research Discipline Proteases And Inhibitors

Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with the Thermo Scientific™ MMP-1 (Collagenase-1) Ab-6, Rabbit Polyclonal Antibody.

Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading connective tissue components. Imbalanced secretion of certain MMP or disturbances in the differential control of MMP by tissue inhibitor of MMPs (TIMPs) are implicated in the invasive potential of malignant tumors. Interstitial collagenase (MMP-1), 72kDa gelatinase A/type IV collagenase (MMP-2), and 92kDa gelatinase B/type IV collagenase (MMP-9) dissolve extracellular matrix (ECM) and may initiate and promote angiogenesis.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Does not react with cow. Others not known.

Epitope: Middle region of MMP-1

Immunogen: A synthetic peptide from the middle region of the human MMP-1

Molecular Weight: 52kDa (unglycosylated) and 57kDa (glycosylated) species of proform of MMP-1 plus 42kDa (unglycosylated) and 47kDa (glycosylated) active form of MMP-1

Positive Control: Conditioned, serum-free medium from (TPA-treated) HFL-1 cells; Placenta; Bladder, breast, ovarian, colon CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO