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Tocris™ ML 337

Selective negative allosteric modulator of mGlu3

$230.05 - $970.32

Specifications

Product Type ML 337
Inhibitors ML 337
Molecular Weight 353.39
Purity >98
View More Specs

 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

498210R

 
tocris™
4982/10
10mg Each for $230.05

498250R

 
tocris™
4982/50
50mg Each for $970.32
Description & Specifications

Specifications

Product Type ML 337
Inhibitors ML 337
Molecular Weight 353.39
Purity >98

Selective negative allosteric modulator of mGlu3 (IC50 = 593nM). Displays no activity at mGlu1, mGlu2 or mGlu4-8 at concentrations up to 30μM. Brain penetrant.

  • Chemical Name: [2-Fluoro-4-[2-(4-methoxyphenyl)ethynyl]phenyl][(3R)-3-hydroxy-1-piperidinyl]methanone
  • Formula: C21H20FNO3
  • CAS Number: 1443118-44-2
  • Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
  • Purity: >98