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MKNK1 (MNK1) Human Protein DFS Item

MKNK1 (MNK1) Human Protein

Manufacturer:  Life Technologies LSPV6023

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Catalog No. PV6023



Description

Description

The Map kinase-interacting kinases (MKNK1 and MKNK2) are activated by Map kinases, regulate protein synthesis by phosphroylating eIF4E on Ser209, and may contribute to tumorigenesis.
Specifications

Specifications

NP_945324
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
Frozen
66.6kDa
96% by SDS-PAGE
–80°C
1 Each
MKNK1 (MNK1)
MKNK1 (MNK1) was pre-diluted in enzyme dilution buffer and assayed in 20mM Tris (pH 7.5), 10mM MgCl2, 1mM EGTA, 1mM Na3VO4, 5mM β-glycerophosphate, 2mM DTT, 0.02% Triton™ X-100, 200μM ATP, 200μM RS domain derived peptide substrate (GRSRSRSRSR) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
MAPKAPK
58nmoles of phosphate transferred to RS domain derived peptide substrate (GRSRSRSRSR) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 3.33μg/mL
GST Tag
0.35mg/mL
Frozen
8569
MKNK1 (MNK1) Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
MKNK1 (MNK1) Human Protein
Kinase assay
Insect
MKNK1 (MNK1) Human Protein
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.