missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Milrinone, 98+%, Thermo Scientific Chemicals

Potent cAMP-specific phosphodiesterase inhibitor

Supplier:  Thermo Scientific Chemicals J62659MF

 View more versions of this product

Catalog No. AAJ62659MF


Description

Description

It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure. Milrinone inhibits the action of phosphodiesterase-3 preventing degradation of cAMP. The corresponding increase in cAMP levels leads to increased activation of protein kinase A. It is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure. Milrinone inhibits the action of phosphodiesterase-3 preventing degradation of cAMP. The corresponding increase in cAMP levels leads to increased activation of protein kinase A. It is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity.

Solubility
Soluble in DMSO. Insoluble in water.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Specifications

Specifications

Milrinone
264°C
C12H9N3O
50 mg
14,6197
Soluble in DMSO; Insoluble in water.
CC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2
211.224
CHEBI:50693
≥98%
78415-72-2
White
MFCD00133539
UN2811
milrinone, primacor, corotrope, corotrop, milrinona, milrinonum, milrinonum latin, milrinona spanish, milrila, unii-ju9yax04c7
PZRHRDRVRGEVNW-UHFFFAOYSA-N
6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile
4197
211.22
Powder

Chemical Identifiers

78415-72-2
211.224
PZRHRDRVRGEVNW-UHFFFAOYSA-N
4197
6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile
C12H9N3O
MFCD00133539
milrinone, primacor, corotrope, corotrop, milrinona, milrinonum, milrinonum latin, milrinona spanish, milrila, unii-ju9yax04c7
CHEBI:50693
CC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2
Safety and Handling

Safety and Handling

GHS H Statement
H300-H311-H331
Fatal if swallowed.
Toxic in contact with skin.
Toxic if inhaled.

P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P311-P312-P330-P361-P363-P501c

H301+H311+H331

DOTInformation : Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.

EINECSNumber : 278-903-6

RTECSNumber : DW1762000

TSCA : No

Recommended Storage : Ambient temperatures

SDS
Documents

Documents

Promotions

Promotions

RUO – Research Use Only