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Thermo Scientific™ Lab Vision™ Microphthalmia (Transcription Factor) (MiTF) Ab-2, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ Microphthalmia (Transcription Factor) (MiTF) Ab-2, Mouse Monoclonal Antibody.

$246.37 - $1,122.94

Specifications

Antigen Microphthalmia (Transcription Factor) (MiTF) Ab-2
Clone D5
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Cross Reactivity Canine
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Products
Catalog Number Mfr. No. Formulation Quantity Price Quantity    

MS772P

 
thermo scientific™ lab vision™
MS-772-P
Purified Ab with BSA and Azide 1mL Each for $1,073.86

MS772P0

 
thermo scientific™ lab vision™
MS-772-P0
Purified Ab with BSA and Azide 100µL Each for $246.37

MS772P1

 
thermo scientific™ lab vision™
MS-772-P1
Purified Ab with BSA and Azide 500µL Each for $693.29

MS772P1ABX

 
thermo scientific™ lab vision™
MS772P1ABX
Ab Without BSA/Azide (Frozen) 100µL Each for $770.53

MS772PABX

 
thermo scientific™ lab vision™
MS-772-PABX
Ab Without BSA/Azide (Frozen) 200µL Each for $1,122.94

MS772R7

 
thermo scientific™ lab vision™
MS-772-R7
Ready-to-use for IHC (UVLP) 7mL Each for $752.84
Description & Specifications

Specifications

Antigen Microphthalmia (Transcription Factor) (MiTF) Ab-2
Clone D5
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Cross Reactivity Canine
Cross Reactivity Human
Cross Reactivity Canine
Cross Reactivity Human
Host Species Mouse
Regulatory Status RUO
Research Discipline Transcription Regulation
Type Primary
Immunogen N-terminal fragment of human Mi protein
Isotype IgG2a kappa

Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ Microphthalmia (Transcription Factor) (MiTF) Ab-2, Mouse Monoclonal Antibody.

Mi is a basic helix-loop-helix-leucine zipper (b-HLH-ZIP) transcription factor implicated in pigmentation, mast cells and bone development. The mutation of Mi causes Waardenburg Syndrome type II in humans. In mice, a profound loss of pigmented cells in the skin eye and inner ear results, as well as osteopetrosis and defects in natural killer and mast cells. There are two known isoforms of Mi differing by 66 amino acids at the NH2 terminus. Shorter forms are expressed in melanocytes and run as two bands at 52kDa and 56kDa, while the longer Mi form runs as a cluster of bands at 60-70kDa in osteoclasts and in B16 melonoma cells (but not other melanoma cell lines), as well as mast cells and heart.

Host Species: Mouse

Clone: D5

Isotype: IgG1/κ

Species Reactivity: Human and Dog. Does not react with mouse and rat. Others not known.

Epitope: N-terminal

Immunogen: N-terminal fragment of human Mi protein

Molecular Weight: 52-56kDa doublet

Positive Control: 501 Mel cells, Melanoma

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not verified)
  • Gel Supershift

Note:

USA: RUO; Int'l: RUO