Thermo Scientific™ Lab Vision™ MHC II (HLA-DR) Ab-1, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry and flow cytometry experiments with the Thermo Scientific™ MHC II (HLA-DR) Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS133P1ABX
Ensure accurate, reproducible results in immunohistochemistry and flow cytometry experiments with the Thermo Scientific™ MHC II (HLA-DR) Ab-1, Mouse Monoclonal Antibody.HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of an α chain (36 kDa) and a β chain (27 kDa). It is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They therefore have a critical role in the initiation of the immune response.
Host Species: Mouse
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: Activated human peripheral blood mononuclear cells
Molecular Weight: 36kDa (α-chain) and 27kDa (β-chain)
Positive Control: Tonsil/lymph node
Cellular Localization: Membrane
- Flow Cytometry
USA: RUO; Int'l: RUO
|MHC II (HLA-DR) Ab-1|
|Flow Cytometry,Immunohistochemistry (Paraffin)|
|Activated human peripheral blood mononuclear cells|