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Thermo Scientific™ Lab Vision™ MHC II (HLA-DR) Ab-1, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry and flow cytometry experiments with the Thermo Scientific™ MHC II (HLA-DR) Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS133P1ABX

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Catalog No. MS133P1ABX

  • / Each
 

Description & Specifications

Specifications

Isotype IgG2b
Applications Flow Cytometry
Applications Immunohistochemistry (Paraffin)
Regulatory Status RUO
Antigen MHC II (HLA-DR) Ab-1
Quantity 100µL
Cross Reactivity Human
Clone LN3
Format Concentrated
Host Species Mouse
Immunogen Activated human peripheral blood mononuclear cells
Conjugate Unlabeled
Concentration 1mg/mL
Classification Monoclonal
Research Discipline Hematopoietic
Type Primary

Ensure accurate, reproducible results in immunohistochemistry and flow cytometry experiments with the Thermo Scientific™ MHC II (HLA-DR) Ab-1, Mouse Monoclonal Antibody.

HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of an α chain (36 kDa) and a β chain (27 kDa). It is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They therefore have a critical role in the initiation of the immune response.

Host Species: Mouse

Clone: LN3

Isotype: IgG2b

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Activated human peripheral blood mononuclear cells

Molecular Weight: 36kDa (α-chain) and 27kDa (β-chain)

Positive Control: Tonsil/lymph node

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO