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MHC Class II (I-A/I-E) Rat anti-Mouse, Alexa Fluor 700, Clone: M5/114.15.2, eBioscience™

Rat Monoclonal Antibody

$143.55 - $361.05

Specifications

Antigen MHC Class II (I-A/I-E)
Clone M5/114.15.2
Host Species Rat
Gene Alias MHC II, IA, IE, I-A/E, IA/IE
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5016917

 
affymetrix
56532180
25μg Each for $143.55

5016918

 
affymetrix
56532182
100μg Each for $361.05
Description & Specifications

Specifications

Antigen MHC Class II (I-A/I-E)
Clone M5/114.15.2
Host Species Rat
Gene Alias MHC II, IA, IE, I-A/E, IA/IE
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Alexa Fluor 700
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The M5/114.15.2 monoclonal antibody reacts with the mouse major histocompatibility complex class II, both I-A and I-E subregion-encoded glycoproteins (I-A b, I-A d, I-A q, I-E d, I-E k, not I-A f, I-A k, or I-A s). It detects a polymorphic determinant present on B cells, monocytes, macrophages, dendritic cells, and activated T lymphocytes from mice carrying the H-2 b, H-2 d, H-2 q, H-2 p, H-2 r and H-2 u but not from mice carrying the H-2 s or H-2 f haplotypes. The M5/114 mAb is reported to inhibit I-A-restricted T cell responses of the H-2 b, H-2 d, H-2 q, H-2 u but not H-2 f, H-2 k, or H-2 s haplotypes.