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Alfa Aesar™ Mevastatin, 98%

Chemical Identifiers

Chemical Name or Material Mevastatin
CAS 73573-88-3
Molecular Formula C23H34O5
Formula Weight 390.52g/mol
MDL Number MFCD05662341
Beilstein 1269441
Merck Index 14,6164
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAJ61357LB0

 
alfa aesar™
J61357-LB0
5mg CALL N/A N/A
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Description & Specifications

Specifications

Quantity 5mg
Color White
Quantity 5mg
Chemical Name or Material Mevastatin
CAS 73573-88-3
Physical Form Crystalline Solid
Assay 98%
Molecular Formula C23H34O5
Formula Weight 390.52g/mol
MDL Number MFCD05662341
Beilstein 1269441
Merck Index 14,6164
Solubility Information Soluble in ethanol at 25 mg/mL and in DMSO at 20mg/ml
Recommended Storage 2° to 8°C
RTECS Number EK7907100

Applications
Mevastatin (Compactin) inhibits HMGCR (HMG-CoA reductase) , induces apoptosis which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Mevastatin causes cells to arrest early in the G1 phase. Mevastatin is a close structural analog of lovastatin and both agents have the same biochemical and pharmacological activities. Mevastatin is inactive in cell-free assays. In cells however, it is hydrolyzed to the active free acid form by intracellular esterases.

Solubility
Soluble in ethanol at 25 mg/mL and in DMSO at 20mg/ml

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C

Safety and Handling

2° to 8°C