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Alfa Aesar™ Methyl phosphorodichloridite, 98%

$95.38 - $95.38

Chemical Identifiers

Chemical Name or Material Methyl phosphorodichloridite
CAS 3279-26-3
Molecular Formula CH3Cl2OP
Linear Formula CH3OPCl2
Formula Weight 132.91
MDL Number MFCD00000524
UN Number UN2920
Beilstein 1697452
Synonym Methyl dichlorophosphite
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAL0458806

  SDS
alfa aesar™
L0458806*
5g Each for $95.38

AAL0458814

  SDS
alfa aesar™
L0458814
25g CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Formula Weight 132.91
Chemical Name or Material Methyl phosphorodichloridite
Assay 98%
Linear Formula CH3OPCl2
Synonym Methyl dichlorophosphite
Boiling Point 92° to 93°C
Flash Point 40°C (104°F)
Health Hazard 3 GHS P Statement
P210-P260-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Recommended Storage 2° to 8°C
Molecular Formula CH3Cl2OP
MDL Number MFCD00000524
CAS 3279-26-3
UN Number UN2920
Beilstein 1697452
Health Hazard 1 Danger
Quantity 5g
Health Hazard 2 GHS H Statement
H314-H318-H226
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.
DOT Information Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUIDS, FLAMMABLE, N.O.S.

Applications
Methyl phosphorodichloridite is a reagent for the phosphite coupling method of oligonucleotide synthesis. It is employed in the preparation of phosphonamidate- and phosphonate-linked phosphonopeptides, 2-(2-iodophenyl)ethyl methyl phosphite derivative of an alcohol, deoxyoligonucleotides on a polymer support, cis- and trans-2-oxo-2-propionyl-1,3,2-oxazaphosphorinane, phosphorodichloridothioates and oxazaphosphorinanes.

Solubility
Reacts with water. Soluble in chloroform, dichloromethane and ethyl acetate.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is sensitive to moisture. Store under dry inert gas.

Safety and Handling

Danger

GHS P Statement
P210-P260-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
Do not breathe dust/fume/gas/mist/vapors/spray.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H314-H318-H226
Causes severe skin burns and eye damage.
Causes serious eye damage.
Flammable liquid and vapor.

2° to 8°C