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Methotrexate, Fisher BioReagents

Manufacturer:  Fisher Scientific Company BP266510

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Catalog No. BP266510


 

Specifications

Description

Methotrexate; 98.0 to 102.0 %; Yellow Powder; Fisher BioReagents; 10mg; Amber Glass; F.W. 454.44; CHNO; mp 195deg.C; CAS: 59-05-2

  • Inhibitor of DNA and RNA synthesis
  • Inhibits the enzyme responsible for synthesizing the folic acid derivative that is necessary for purine and pyrimidine synthesis
  • The lack of purines and pyrimidines  impacts the synthesis of DNA, RNA, and proteins
  • Referenced for use in antitumor studies and other studies of biological pathways
  • Intended for research use only
Description & Specifications

Specifications

454.44
195°C
15, 6057
C20H22N8O5
12% Max.
Pass Test
Amber Glass
59-05-2
0.1% max.
Methotrexate
Powder/Solid
10mg
98.0 to 102.0%
Yellow
>195°C
+19.0 to +24.0° (+ or -)
98.0 to 102.0 %
Meets Requirements
Amethopterin

Chemical Identifiers

59-05-2
98.0 to 102.0 %
454.44
Methotrexate
Powder/Solid
C20H22N8O5
Amethopterin
98.0 to 102.0%

Safety and Handling

SDS & Safety Documents

DANGER!

Emergency Overview
Toxic if swallowed. This substance has caused adverse reproductive and fetal effects in humans. May cause heritable genetic damage. Liver and kidney injuries may occur. Hygroscopic. Use only under a chemical fume hood. Use personal protective equipment. Do not breathe dust. Do not get in eyes, on skin, or on clothing. Wash off immediately with plenty of water for at least 15 minutes. Obtain medical attention. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Obtain medical attention.

NFPA

Health:3
Flammability:0
Instability:1

DOTInformation : DOT Class 6.1, : Poison

Recommended Storage : 0°C