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Thermo Scientific™ MethElute™ Reagent (TMPAH)

For accurate, sensitive on-column methylation use Thermo Scientific™ MethElute™ Reagent (TMPAH).

$418.00 - $933.51


For Use With GC
Hazards Flammable, Toxic
Standard Components Trimethylanilinium hydroxide in Methanol
Standard Concentration 0.2M
Storage Room Temperature
View More Specs


Limited warranty period: Subject to all warranty requirements and exclusions set out in our Terms and Conditions of Sale, this product is warranted from the date we ship the product and for ninety (90) days thereafter. Disclaimer to internal research use restriction: Any restrictions on the purchaser to utilize the product(s) for internal research purposes only does not apply to the product(s) on the web pages associated with this statement.

Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
PI49300 Thermo Scientific™
10mL Each for $418.00
PI49301 Thermo Scientific™
12 x 1mL Pack of 12 Each for $933.51


For accurate, sensitive, on-column methylation and detection by GC analysis use Thermo Scientific™ MethElute™ Reagent (TMPAH). It is ideally suited for the quantitative methylation and detection of barbiturates, sedatives, xanthine bases, phenolic alkaloids, and phenytoin, giving a single quantitative peak for each substance. When the reagent is heated with drug-containing extracts, serum, or urine the drugs containing reactive amino, hydroxyl, and carboxyl functions will be methylated at the reactive sites.

Performance Characteristics

Accuracy comparable or better than the UV/TLC method (GC is superior to UV/TLC when phenobarbitol and phenytoin present)

High precision, with coefficient of variation of 5% or less

High sensitivity; barbiturates deteced down to 0.2 mg/dL

Description & Specifications


Trimethylanilinium hydroxide in Methanol
Room Temperature
Flammable, Toxic