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Alfa Aesar™ Meclizine dihydrochloride monohydrate

Antiemetic and H1-histamine receptor antagonist

$46.72 - $388.61

Chemical Identifiers

CAS 31884-77-2
Molecular Formula C25H31Cl3N2O
Molecular Weight (g/mol) 481.886
MDL Number MFCD00058199
InChI Key KDLHYOMCWBWLMM-UHFFFAOYSA-N
Synonym meclizine hydrochloride, meclizine dihydrochloride monohydrate, meclizine hcl, antivert tn, c25h27cln2.2hcl.h2o, 1-p-chloro-alpha-phenylbenzyl-4-m-methylbenzyl piperazine dihydrochloride monohydrate, 1-4-chlorophenyl-phenylmethyl-4-3-methylphenyl methyl piperazine hydrate dihydrochloride, piperazine, 1-4-chlorophenyl phenylmethyl-4-3-methylphenyl methyl-, dihydrochloride, monohydrate, meclizine hcl hydrate, meclizine hydrochloride usan:jan
PubChem CID 173612
IUPAC Name 1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine;hydrate;dihydrochloride
SMILES CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.O.Cl.Cl
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ6246403 View Documents Alfa Aesar™
J6246403
1g Each for $46.72
 
AAJ6246406 View Documents Alfa Aesar™
J6246406
5g Each for $215.89
 
AAJ6246409 View Documents Alfa Aesar™
J6246409
10g Each for $388.61
 
Description

Description

Applications
Antiemetic and H1-histamine receptor antagonistMeclizine dihydrochloride monohydrate acts as an antiemetic. It is also used for the prevention and treatment of nausea during pregnancy. In addition to this, it is used in radiation sickness, vomiting or dizziness associated with motion sickness.

Solubility
Insoluble in water.

Notes
Incompatible with heat and oxidizing agents.
Specifications

Chemical Identifiers

31884-77-2
481.886
KDLHYOMCWBWLMM-UHFFFAOYSA-N
173612
CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.O.Cl.Cl
C25H31Cl3N2O
MFCD00058199
meclizine hydrochloride, meclizine dihydrochloride monohydrate, meclizine hcl, antivert tn, c25h27cln2.2hcl.h2o, 1-p-chloro-alpha-phenylbenzyl-4-m-methylbenzyl piperazine dihydrochloride monohydrate, 1-4-chlorophenyl-phenylmethyl-4-3-methylphenyl methyl piperazine hydrate dihydrochloride, piperazine, 1-4-chlorophenyl phenylmethyl-4-3-methylphenyl methyl-, dihydrochloride, monohydrate, meclizine hcl hydrate, meclizine hydrochloride usan:jan
1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine;hydrate;dihydrochloride

Specifications

White
1g
C25H31Cl3N2O
14,5777
KDLHYOMCWBWLMM-UHFFFAOYSA-N
1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine;hydrate;dihydrochloride
173612
Powder
210°C to 213°C
31884-77-2
MFCD00058199
meclizine hydrochloride, meclizine dihydrochloride monohydrate, meclizine hcl, antivert tn, c25h27cln2.2hcl.h2o, 1-p-chloro-alpha-phenylbenzyl-4-m-methylbenzyl piperazine dihydrochloride monohydrate, 1-4-chlorophenyl-phenylmethyl-4-3-methylphenyl methyl piperazine hydrate dihydrochloride, piperazine, 1-4-chlorophenyl phenylmethyl-4-3-methylphenyl methyl-, dihydrochloride, monohydrate, meclizine hcl hydrate, meclizine hydrochloride usan:jan
CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.O.Cl.Cl
481.886
481.89 (463.88 Anhydrous)
Meclizine dihydrochloride monohydrate
Safety and Handling

Safety and Handling

GHS H Statement
H361-H302
Suspected of damaging fertility or the unborn child.
Harmful if swallowed.

GHS P Statement
P281-P264-P301+P312-P308+P313-P405-P501a
Use personal protective equipment as required.
Wash thoroughly after handling.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
IF exposed or concerned: Get medical advice/attention.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

TSCA : TSCA

Recommended Storage : −30° to −10°C