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MD-2 Mouse anti-Human, Clone: 9B4, eBioscience™

Mouse Monoclonal Antibody

$143.88 - $328.68

Specifications

Antigen MD-2
Clone 9B4
Host Species Murine
Gene Alias MD2; Toll-like Receptor
Applications Immunoprecipitation
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5013883 Life Technologies
LS14992880
25μg Each for $143.88
5013884 Life Technologies
LS14992882
100μg Each for $328.68
Specifications

Description

The 9B4 antibody reacts with human MD-2, an approximately 30kDa molecule, which physically associates with the extracellular domain of TLR4. MD-2 is essential for correct intracellular distribution and LPS-recognition of TLR4 since in MD-2(-/-) embryonic fibroblasts, TLR4 was not able to reach the plasma membrane and predominantly resided in the Golgi apparatus, whereas TLR4 was distributed at the leading edge surface of cells in wild-type embryonic fibroblasts. MD-2(-/-) mice do not respond to LPS, do survive endotoxic shock but are susceptible to Salmonella typhimurium infection.
Description & Specifications

Specifications

MD-2
Murine
Immunoprecipitation
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
9B4
MD2; Toll-like Receptor
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer