Please login to your online account to display your discounted pricing

Tocris™ (±)-McN 5652

Potent, orally active 5-HT uptake inhibitor. Also inhibits noradrenalin and dopamine uptake in vitro

$237.76 - $1,001.17

Specifications

Product Type (±)-McN 5652
Inhibitors (±)-McN 5652
Molecular Weight 295.44
Purity >95
View More Specs

 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

214810R

 
tocris™
2148/10
10mg Each for $237.76

214850

 
tocris™
2148/50
50mg Each for $1,001.17
Description & Specifications

Specifications

Product Type (±)-McN 5652
Inhibitors (±)-McN 5652
Molecular Weight 295.44
Purity >95

Potent, high affinity serotonin re-uptake inhibitor; selective in vivo. Displays moderate selectivity over noradrenalin and dopamine re-uptake in vitro (Ki values are 0.68, 2.9 and 36.8nM for inhibition of serotonin, noradrenalin and dopamine uptake respectively in rat brain synaptosomes). Potently potentiates 5-HT-induced effects in vivo following oral administration. Biological activity resides predominantly in the (+)-enantiomer.

  • Chemical Name: (6R,10bS)-rel-1,2,3,5,6,10b-Hexahydro-6-[4-(methylthio)phenyl]-pyrrolo[2,1-a]isoquinoline
  • Formula: C19H21NS
  • CAS Number: 96795-89-0
  • Solubility: Soluble to 50mM in 1eq. HCl and to 75mM in DMSO