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Thermo Scientific™ Lab Vision™ Mcl-1 Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ Mcl-1 Ab-1, Mouse Monoclonal Antibody.

$260.76 - $1,390.55

Specifications

Antigen Mcl-1 Ab-1
Clone RC13
Applications Immunoprecipitation
Applications Western Blotting
Applications Immunoprecipitation
View More Specs
Products
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity    

MS681B

 
thermo scientific™ lab vision™
MS-681-B
400ug/mL Biotin 1mL Each for $1,390.55

MS681B0

 
thermo scientific™ lab vision™
MS-681-B0
400ug/mL Biotin 100µL Each for $349.45

MS681B1

 
thermo scientific™ lab vision™
MS-681-B1
400ug/mL Biotin 500µL Each for $930.22

MS681P

 
thermo scientific™ lab vision™
MS-681-P
400ug/mL Unlabeled 1mL Each for $1,068.31

MS681P0

 
thermo scientific™ lab vision™
MS-681-P0
400ug/mL Unlabeled 100µL Each for $260.76

MS681P1

 
thermo scientific™ lab vision™
MS-681-P1
400ug/mL Unlabeled 500µL Each for $737.88

MS681P1ABX

 
thermo scientific™ lab vision™
MS681P1ABX
1mg/mL Unlabeled 100µL Each for $784.49

MS681PABX

 
thermo scientific™ lab vision™
MS-681-PABX
1mg/mL Unlabeled 200µL Each for $1,125.86
Description & Specifications

Specifications

Antigen Mcl-1 Ab-1
Clone RC13
Applications Immunoprecipitation
Applications Western Blotting
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Regulatory Status RUO
Research Discipline Apoptosis
Type Primary
Immunogen Recombinant human Mcl-1 protein corresponding to aa 1-327
Isotype IgG2a kappa

Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ Mcl-1 Ab-1, Mouse Monoclonal Antibody.

Mcl-1 (Myeloid cell leukemia-1) is a member of the bcl-2 family. The carboxy terminal of Mcl-1 and bcl-2 share significant sequence homology. Expression of Mcl-1 is increased upon exposure of ML-1 cells to various types of DNA damaging agents (e.g. ionizing radiation, ultraviolet radiation, and alkylating drugs) along with increases in GADD45 and Bax and a decrease in bcl-2. Enhanced expression of Mcl-1, prominently associated with mitochondria, complements the continued expression of bcl-2 in ML-1 cells undergoing differentiation. Like bcl-2, Mcl-1 has the capacity to promote cell viability under conditions that otherwise cause apoptosis.

Host Species: Mouse

Clone: RC13

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: aa 1-327

Immunogen: Recombinant human Mcl-1 protein corresponding to aa 1-327

Molecular Weight: 42kDa

Positive Control: Raji cells, Spleen or tonsil

Cellular Localization: Predominantly nuclear; occasionally cytoplasmic

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO