Thermo Scientific™ Lab Vision™ Mast Cell Tryptase Ab-2, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ Mast Cell Tryptase Ab-2, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS1216PABX
Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ Mast Cell Tryptase Ab-2, Mouse Monoclonal Antibody.Mast cells contain a number of preformed chemical mediators such as histamine, chymase, carboxypeptidase and proteolytic tryptase. A substantial quantity of tryptase is estimated to be found in mast cells of skin and lung and suggestes this enzyme plays a major role in mast cell mediated events. In vitro studies indicate tryptase can cleave C3 to form C3a anaphylatoxin, inactivate fibrinogen as a coaguable substrate for thrombin and activate latent collagenase. Human mast cell tryptase has considerable potential as a marker for mast cell activation as well as being a mediator of inflammation.
Host Species: Mouse
Species Reactivity: Human, Monkey, Dog and Cat. Others not known.
Epitope: Not determined
Immunogen: Human mast cell tryptase purified from human lung tissues
Positive Control: Tonsil
Cellular Localization: Cytoplasmic
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
USA: RUO; Int'l: RUO
|Mast Cell Tryptase Ab-2|
|Ab without BSA/Azide (Frozen)|
|Immunohistochemistry (Paraffin),Western Blotting|
|Human mast cell tryptase purified from human lung tissues|