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Thermo Scientific™ Lab Vision™ Mast Cell Tryptase Ab-2, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ Mast Cell Tryptase Ab-2, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1216PABX

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Catalog No. MS1216PABX

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Description & Specifications

Specifications

Cross Reactivity Canine
Cross Reactivity Feline
Cross Reactivity Human
Cross Reactivity Non-Human Primate
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Isotype IgG1
Quantity 200µL
Format Concentrated
Immunogen Human mast cell tryptase purified from human lung tissues
Regulatory Status RUO
Clone AA1
Antigen Mast Cell Tryptase Ab-2
Host Species Mouse
Formulation Ab without BSA/Azide (Frozen)
Research Discipline Enzyme
Type Primary
Classification Monoclonal
Concentration 1mg/mL
Conjugate Unlabeled
Item Description 200uL; 1mg/mL; Purified w/o BSA, azide

Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ Mast Cell Tryptase Ab-2, Mouse Monoclonal Antibody.

Mast cells contain a number of preformed chemical mediators such as histamine, chymase, carboxypeptidase and proteolytic tryptase. A substantial quantity of tryptase is estimated to be found in mast cells of skin and lung and suggestes this enzyme plays a major role in mast cell mediated events. In vitro studies indicate tryptase can cleave C3 to form C3a anaphylatoxin, inactivate fibrinogen as a coaguable substrate for thrombin and activate latent collagenase. Human mast cell tryptase has considerable potential as a marker for mast cell activation as well as being a mediator of inflammation.

Host Species: Mouse

Clone: AA1

Isotype: IgG1

Species Reactivity: Human, Monkey, Dog and Cat. Others not known.

Epitope: Not determined

Immunogen: Human mast cell tryptase purified from human lung tissues

Positive Control: Tonsil

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO