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Thermo Scientific™ Lab Vision™ Mast Cell Tryptase Ab-2, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ Mast Cell Tryptase Ab-2, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1216P1ABX

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Catalog No. MS1216P1ABX

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Description & Specifications

Specifications

Host Species Mouse
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Regulatory Status RUO
Format Concentrated
Cross Reactivity Canine
Cross Reactivity Feline
Cross Reactivity Human
Cross Reactivity Non-Human Primate
Antigen Mast Cell Tryptase Ab-2
Quantity 100µL
Immunogen Human mast cell tryptase purified from human lung tissues
Isotype IgG1
Clone AA1
Formulation Ab without BSA/Azide (Frozen)
Research Discipline Enzyme
Type Primary
Conjugate Unlabeled
Classification Monoclonal
Concentration 1mg/mL
Item Description 100uL; 1mg/mL; Purified w/o BSA, azide

Ensure accurate, reproducible results in immunohistochemistry experiments with the Thermo Scientific™ Mast Cell Tryptase Ab-2, Mouse Monoclonal Antibody.

Mast cells contain a number of preformed chemical mediators such as histamine, chymase, carboxypeptidase and proteolytic tryptase. A substantial quantity of tryptase is estimated to be found in mast cells of skin and lung and suggestes this enzyme plays a major role in mast cell mediated events. In vitro studies indicate tryptase can cleave C3 to form C3a anaphylatoxin, inactivate fibrinogen as a coaguable substrate for thrombin and activate latent collagenase. Human mast cell tryptase has considerable potential as a marker for mast cell activation as well as being a mediator of inflammation.

Host Species: Mouse

Clone: AA1

Isotype: IgG1

Species Reactivity: Human, Monkey, Dog and Cat. Others not known.

Epitope: Not determined

Immunogen: Human mast cell tryptase purified from human lung tissues

Positive Control: Tonsil

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting

Note:

USA: RUO; Int'l: RUO