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MAP3K7/MAP3K7IP1 (TAK1-TAB1) Recombinant Human Protein DFS Item

MAP3K7/MAP3K7IP1 (TAK1-TAB1) Recombinant Human Protein

Manufacturer:  Life Technologies LSPV4394

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Catalog No. PV4394



Description

Description

MAP3K7 (TAK1) controls transcription regulation and apoptosis, and is implicated in inflammatory disease and rheumatoid arthritis. Fusion of MAP3K7 to MAP3K7IP1 (TAB1) activates MAP3K7.
Specifications

Specifications

NP_663306, NP_006107
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
MAP3K7/MAP3K7IP1 (TAK1-TAB1) Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
MAP3K7/MAP3K7IP1 (TAK1-TAB1) Recombinant Human Protein
Kinase assay
Baculovirus
aa 437 to 504
39nmoles of phosphate transferred to myelin basic protein (MBP) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 8.33μg/mL
His Tag
0.34mg/mL
45.8kDa
55% by SDS-PAGE
–80°C
1 Each
MAP3K7/MAP3K7IP1 (TAK1-TAB1)
MAP3K7-MAP3K7IP1 (TAK1-TAB1) was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β−glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 100 μM ATP, 500μg/mL myelin basic protein (MBP) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinases & Inhibitors
MLK kinase family
MAP3K7/MAP3K7IP1 (TAK1-TAB1) Recombinant Human Protein
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.