Invitrogen™ MAP3K10 (MLK2) Recombinant Human Protein
MAP3K10 (MLK2) is a serine/threonine kinase which has been shown to activate MAPK8/JNK and MKK4/SEK1.
Manufacturer: Invitrogen™ LSPV4195
The MAP3K10 (MLK2) kinase itself can be phoshorylated, and is thus activated by JNK kinases. MAP3K10 functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
|Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.|
|MLK Kinase Family|
|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|
|50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol|
|RUO - research use only|