missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

MAP3K10 (MLK2) Recombinant Human Protein DFS Item

MAP3K10 (MLK2) Recombinant Human Protein

Manufacturer:  Life Technologies LSPV3877

Catalog No. PV3877



Description

Description

MAP3K10 (MLK2) is a serine⁄threonine kinase which has been shown to activate MAPK8⁄JNK and MKK4⁄SEK1. This kinase itself can be phoshorylated, and is thus activated by JNK kinases. MAP3K10 functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
Specifications

Specifications

NP_002437
Cell viability, proliferation and function, pharma and biopharma, protein assays and analysis, target and lead identification and validation
131.2kDa
60% by SDS-PAGE
–80°C
1 Each
MAP3K10 (MLK2)
MAP3K10 (MLK2) was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 100μM ATP, 450μg/mL myelin basic protein (MBP) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
MLK
59nmoles of phosphate transferred to myelin basic protein (MBP) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 8.33μg/mL
GST Tag
0.34mg/mL
114294, 4294
MAP3K10 (MLK2) Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
MAP3K10 (MLK2) Recombinant Human Protein
Kinase assay
Baculovirus
MAP3K10 (MLK2) Recombinant Human Protein
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.