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Thermo Scientific MAGE-1 Ab-4, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MAGE-1 Ab-4, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific MS1067PABX

 View more versions of this product

Catalog No. MS1067PABX


 

Specifications

Description

Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MAGE-1 Ab-4, Mouse Monoclonal Antibody.

Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy

Host Species: Mouse

Clone: MA454

Isotype: IgG1/κ

Species Reactivity: Human, Dog and Rat. Others not known.

Immunogen: Partially purified, full-length recombinant human MAGE-1 protein

Molecular Weight: 42-46kDa

Positive Control: Colo32 cells germ cells in testis

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin only)
  • Western Blotting
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

MAGE-1 Ab-4
Monoclonal
1mg/mL
Canine,Human,Rat
Ab Without BSA/Azide (Frozen)
Partially purified, full length recombinant human MAGE-1 protein
200μL
Cancer and Tumor Biology
Monoclonal
Immunofluorescence,Immunohistochemistry (Paraffin),Western Blotting
MA454
Unlabeled
Concentrated
Murine
IgG2a kappa
RUO
Primary
Canine,Human,Rat