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Thermo Scientific™ Lab Vision™ MAGE-1 Ab-4, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MAGE-1 Ab-4, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1067P1ABX

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Catalog No. MS1067P1ABX

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Description & Specifications

Specifications

Antigen MAGE-1 Ab-4
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Classification Monoclonal
Clone MA454
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Canine
Cross Reactivity Human
Cross Reactivity Rat
Format Concentrated
Formulation Ab Without BSA/Azide (Frozen)
Host Species Mouse
Immunogen Partially purified, full length recombinant human MAGE-1 protein
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Type Primary

Ensure accurate, reproducible results in experiments with the Thermo Scientific™ MAGE-1 Ab-4, Mouse Monoclonal Antibody.

Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy

Host Species: Mouse

Clone: MA454

Isotype: IgG1/κ

Species Reactivity: Human, Dog and Rat. Others not known.

Immunogen: Partially purified, full-length recombinant human MAGE-1 protein

Molecular Weight: 42-46kDa

Positive Control: Colo32 cells germ cells in testis

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin only)
  • Western Blotting
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO