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Thermo Scientific™ MAbPac™ SCX-10 LC Columns


Use these strong cation-exchange columns for high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants.

Manufacturer: thermo scientific™  075602

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 Disclaimers

Limited warranty period: Subject to all warranty requirements and exclusions set out in our Terms and Conditions of Sale, this product is warranted from the date we ship the product and for ninety (90) days thereafter. Disclaimer to internal research use restriction: Any restrictions on the purchaser to utilize the product(s) for internal research purposes only does not apply to the product(s) on the web pages associated with this statement.

Catalog No. DX075602

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Description & Specifications

Specifications

Column Format Analytical Column
Diameter (Metric) 4mm
Type Analytical Column
Stationary Phase Sulfonate
USP Type N/A
Technique Monoclonal Antibody/Cation Exchange
Particle Size 10µm
Solvents 50% Acetonitrile
Max. Pressure 3000psi
Temperature 60°C
Flow Rate 0.2 to 2.0mL/min.
Carbon Load -
Pore Size Non-porous
Packing Material Spherical, non-porous polymer
Length (Metric) 150mm
pH 2 to 12
Endcapped -
Surface Area -
Column Type Ion Exchange

Use Thermo Scientific™ MAbPac™ SCX-10 LC Columns for high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants. The unique nonporous pellicular resin provides the resolving power to separate mAb variants that differ by as little as one charged residue. A hydrophilic layer surrounds the polymeric beads and eliminates hydrophobic interactions with the resin, resulting in very efficient peaks. A proprietary grafted cation-exchange surface provides pH selectivity control for high-resolution separations.

Superior Performance for mAb Variant Analysis

  • Exceptionally high resolution for mAb variants
  • Ideal for characterization and quality control assessment of mAbs
  • Well-suited for stability studies, mAb therapeutic method development and high-throughput screening
  •  Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing
  • Meets the regulatory requirements for biopharmaceutical characterization
Multiple Sizes Available
  • Available in 3, 5 and 10μm particle sizes in standard and UHPLC formats
  • Smaller-particle-size columns provide the same resolution as the 10μm columns, but with significantly faster analysis time