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Thermo Scientific™ MAbPac™ SCX-10 LC Columns

Use these strong cation-exchange columns for high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants.

Manufacturer: thermo scientific™  074625

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Catalog No. DX074625


Description & Specifications


Column Type Ion Exchange
Type Analytical Column
Carbon Load -
USP Type N/A
Endcapped -
Flow Rate 0.2 to 2.0mL/min.
Max. Pressure 3000psi
Packing Material Spherical, non-porous polymer
Particle Size 10µm
Temperature 60°C
Pore Size Non-porous
pH 2 to 12
Stationary Phase Sulfonate
Solvents 50% Acetonitrile
Surface Area -
Length (Metric) 250mm
Technique Monoclonal Antibody/Cation Exchange
Column Format Analytical Column
Diameter (Metric) 4mm

Use Thermo Scientific™ MAbPac™ SCX-10 LC Columns for high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants. The unique nonporous pellicular resin provides the resolving power to separate mAb variants that differ by as little as one charged residue. A hydrophilic layer surrounds the polymeric beads and eliminates hydrophobic interactions with the resin, resulting in very efficient peaks. A proprietary grafted cation-exchange surface provides pH selectivity control for high-resolution separations.

Superior Performance for mAb Variant Analysis

  • Exceptionally high resolution for mAb variants
  • Ideal for characterization and quality control assessment of mAbs
  • Well-suited for stability studies, mAb therapeutic method development and high-throughput screening
  •  Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing
  • Meets the regulatory requirements for biopharmaceutical characterization
Multiple Sizes Available
  • Available in 3, 5 and 10μm particle sizes in standard and UHPLC formats
  • Smaller-particle-size columns provide the same resolution as the 10μm columns, but with significantly faster analysis time