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Thermo Scientific™ MAbPac™ SCX-10 LC Columns

Use these strong cation-exchange columns for high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants.

Manufacturer: thermo scientific™  075604

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Limited warranty period: Subject to all warranty requirements and exclusions set out in our Terms and Conditions of Sale, this product is warranted from the date we ship the product and for ninety (90) days thereafter. Disclaimer to internal research use restriction: Any restrictions on the purchaser to utilize the product(s) for internal research purposes only does not apply to the product(s) on the web pages associated with this statement.

Catalog No. DX075604

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Description & Specifications


Column Format Analytical Column
Diameter (Metric) 2mm
Particle Size 10µm
Carbon Load -
Column Type Ion Exchange
USP Type N/A
Packing Material Spherical, non-porous polymer
Stationary Phase Sulfonate
Max. Pressure 3000psi
Solvents 50% Acetonitrile
Endcapped -
Flow Rate 0.1 to 0.5mL/min.
pH 2 to 12
Length (Metric) 250mm
Pore Size Non-porous
Type Analytical Column
Technique Monoclonal Antibody/Cation Exchange
Temperature 60°C
Surface Area -

Use Thermo Scientific™ MAbPac™ SCX-10 LC Columns for high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants. The unique nonporous pellicular resin provides the resolving power to separate mAb variants that differ by as little as one charged residue. A hydrophilic layer surrounds the polymeric beads and eliminates hydrophobic interactions with the resin, resulting in very efficient peaks. A proprietary grafted cation-exchange surface provides pH selectivity control for high-resolution separations.

Superior Performance for mAb Variant Analysis

  • Exceptionally high resolution for mAb variants
  • Ideal for characterization and quality control assessment of mAbs
  • Well-suited for stability studies, mAb therapeutic method development and high-throughput screening
  •  Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing
  • Meets the regulatory requirements for biopharmaceutical characterization
Multiple Sizes Available
  • Available in 3, 5 and 10μm particle sizes in standard and UHPLC formats
  • Smaller-particle-size columns provide the same resolution as the 10μm columns, but with significantly faster analysis time